Esra Erkut - Dissertation du lauréat, 2022
My passion for genetics first began in high school, as it combined my interest in human health with my aptitude for analytical problem solving. Accordingly, I completed a BSc specializing in Molecular Genetics at the University of Alberta, graduating with distinction (3.94/4). Involvement in research was a priority during my degree, as I undertook two long-term research projects. First, I investigated methods to improve the mechanical strength of 3D-bioprinted human nasal cartilage. Next, I helped develop a novel therapeutic for spinal muscular atrophy, a fatal infantile disorder. I contributed to seven refereed articles, including three as first author, and presented at eight conferences culminating in three first-place prizes. Additionally, I contributed to eSkip Finder, a machine learning tool that helps researchers design treatments for genetic neuromuscular diseases. I was awarded six competitive accolades for involvement in science outreach, leadership, research, and academic excellence.
I am now a first-year MSc student in Molecular Genetics at the University of Toronto. My research focuses on unraveling the mysteries of “non-coding” regions in the human genome, harnessing the power of computational biology and animal models. I believe these unexplored regions may contribute to human disease, with a particular interest in congenital heart disease as it affects ~1% of newborns.
Following my studies, I plan to become a professor and direct my own research lab, where I can help train the next generation of scientists. I will focus on molecular therapies to tackle widespread diseases, as my goal is to advance medicine through research.